Methylation — Genomics & DNA

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Methylation Genetics Panel

Focused genetic analysis of methylation pathway variants including MTHFR, MTR, MTRR, BHMT, CBS, and related SNPs. Essential for understanding folate metabolism, homocysteine management, and neurotransmitter synthesis.

Clinical Applications

Methylation support protocols, B-vitamin optimization, homocysteine management, mood and cognitive support, and preconception planning.

Quick Facts

Biomarkers12
Turnaround10-14 days
PartnerCLIA Labs
FastingNot required

Specimen Type

Cheek Swab

Min. Plan Required

professional

Key Biomarkers

12 biomarkers analyzed — here are the highlights

MTHFR C677T

Primary methylation variant — folate conversion

MTHFR A1298C

Secondary methylation variant — BH4 pathway

MTR

Methionine synthase — B12-dependent methylation

MTRR

Methionine synthase reductase — B12 recycling

CBS

Cystathionine beta-synthase — transsulfuration

BHMT

Betaine-homocysteine methyltransferase — alternate pathway

Ideal For

This test is designed for the following practice types and clinical scenarios

Naturopathic doctors
Functional medicine
Fertility specialists
Mental health practitioners
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